Abstract: The entrenchment of the neoliberal state and rise of populist leaders has marginalized the role of voluntary organizations in society. This presents significant challenges for nonprofit leaders in economically challenged areas as it erodes their ability to protect and serve vulnerable populations. Attention turns to maintaining hard fought gains at the expense of making progress. Yet doing so requires new skills and leadership styles to manage organizational change where innovation and transformation are key. Based on 42 qualitative interviews with disability nonprofit leaders in Atlantic Canada, our study aims to characterize this transformation. Using Szerb’s (2003) key attributes of entrepreneurship that distinguish between entre-, intra-, and interpreneurs, we find disability leaders have become interpreneurs. We find a strong emphasis on networked service delivery underscoring shared goals, risks and responsibilities, and resources. For disability leaders, cultivating relationships and strong communication skills are essential. In the face of populist desires for state retrenchment, we question how long this collective response can hold given ongoing economic challenges.